Mets at Nationals Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for August 21

It's Thursday, August 21 and the Mets (67-59) are in Washington to take on the Nationals (51-75).

Sean Manaea is slated to take the mound for New York against MacKenzie Gore for Washington.The series is split after Washington took the second game, 5-4 to follow up an 8-1 loss.

The loss snapped the Mets three-game winning streak that followed a rough patch (5-12 over the last 17 games).

Let's dive into the matchup and find a sweat or two.

Weve got all the info and analysis you need to know ahead of the game, including the latest info on how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.Game details & how to watch Mets at NationalsDate: Thursday, August 21, 2025Time: 4:05PM ESTSite: Nationals ParkCity: Washington, DCNetwork/Streaming: SNY, MASNNever miss a second of the action and stay up-to-date with all the latest team stats and player news.

Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.Odds for the Mets at the NationalsThe latest odds as of Thursday:Moneyline: Mets (-140), Nationals (+118)Spread: Mets -1.5Total: 8.0 runsProbable starting pitchers for Mets at NationalsPitching matchup for August 21, 2025: Sean Manaea vs.

MacKenzie GoreMets: Sean Manaea, (1-1, 4.78 ERA)Last outing: 7.20 ERA, 4 Earned Runs Allowed, 6 Hits Allowed, 1 Walks, and 7 StrikeoutsNationals: MacKenzie Gore, (5-12, 4.04 ERA)Last outing: 3.00 ERA, 2 Earned Runs Allowed, 4 Hits Allowed, 2 Walks, and 7 StrikeoutsRotoworld still has you covered with all the latest MLB player news for all 30 teams.

Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!Expert picks & predictions for tonights game between the Mets and the Nationals Rotoworld Best BetPlease bet responsibly.

If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.Here are the best bets our model is projecting for Thursdays game between the Mets and the Nationals:Moneyline: NBC Sports Bet is recommending a play on the New York Mets on the Moneyline.Spread: NBC Sports Bet is leaning towards a play ATS on the Washington Nationals at +1.5.Total: NBC Sports Bet is recommending a play on the over on the Game Total of 8.0.Want even more MLB best bets and predictions from our expert staff & tools? Check out the Expert MLB Predictions page from NBC.Top betting trends & insights to know ahead of Mets at NationalsNew York is 3-1 in the last 4 gamesNew York is 5-12 over the last 17 gamesWashington is 5-5 over the last 10 gamesThe Nationals have a losing record (10-20) in divisional matchups this seasonIt has been 3 games since the Mets last failed to cover the Run LineIf youre looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!Follow our experts on socials to keep up with all the latest content from the staff:Jay Croucher (@croucherJD)Drew Dinsick (@whale_capper)Vaughn Dalzell (@VmoneySports)Trysta Krick (@Trysta_Krick).

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