College Football Betting Odds Week 3: Picks Against the Spread for Top 25 Schedule

History tells us that the top-ranked Georgia Bulldogs do not have to worry about an upset in their SEC opener against the Kentucky Wildcats in Week 3.

UGA has a long-running domination of the series with Kentucky, and recently, the Wildcats have struggled to even score one touchdown per game on the Bulldogs defense.

Georgia and some of the other top-ranked teams will try to get out of Week 3 unscathed.

Usually the college football weeks without a marquee game can become chaotic, but UGA should avoid that.

The Ole Miss Rebels should not be in the upset conversation either.

Jaxson Dart has led the Ole Miss offense to 128 points in the first two weeks and a road trip to Wake Forest should just be another place for the offense to dominate.

Friday, September 13 No.

20 Arizona at No.

14 Kansas State (-7) (8 p.m.

ET, Fox) Saturday, September 14 No.

4 Alabama (-16) at Wisconsin (Noon ET, Fox) No.

13 Oklahoma State (-18) at Tulsa (Noon ET, ESPN2) No.

16 LSU (-6.5) at South Carolina (Noon ET, ABC) Arkansas State at No.

17 Michigan (-23.5) (Noon ET, BTN) No.

24 Boston College at No.

6 Missouri (-16) (12:45 p.m.

ET, SEC Network) No.

9 Oregon (-16.5) at Oregon State (3:30 p.m.

ET, Fox) Ball State at No.

10 Miami (-36.5) (3:30 p.m.

ET, ACC Network) Tulane at No.

15 Oklahoma (-13) (3:30 p.m.

ET, ESPN) No.

18 Notre Dame (-9.5) at Purdue (3:30 p.m.

ET, NBC) No.

12 Utah (-18.5) at Utah State (4:30 p.m.

ET, CBS Sports Network) No.

5 Ole Miss (-21.5) at Wake Forest (6:30 p.m.

ET, CW Network) UTSA at No.

2 Texas (-35.5) (7 p.m.

ET, ESPN) No.

1 Georgia (-22) at Kentucky (7:30 p.m.

ET, ABC) Northern Iowa at No.

23 Nebraska (-32.5) (7:30 p.m.

ET, BTN) Kent State at No.

7 Tennessee (-49) (7:45 p.m.

ET, SEC Network) Odds via DraftKings Sportsbook .

Georgia has not lost to Kentucky since 2009.

The Bulldogs have outscored the Wildcats 132-35 in their last five head-to-head meetings in SEC play.

Georgia's trips to Lexington have produced closer games on the final scoreboard, but the 14-3 and 16-6 wins in 2020 and 2022 were not close.

Carson Beck led UGA to a 51-13 thumping of Mark Stoops' Wildcats last season in Athens.

A similar score could be in the cards for Saturday night in Lexington.

Kentucky looked lifeless in its 31-6 loss to the South Carolina Gamecocks in Week 2.

If the Wildcats can't play with South Carolina, a mid-tier SEC team at best, they certainly can't keep pace with UGA.

Georgia's defense has not allowed a touchdown in two games against Tennessee and Tennessee Tech.

It won those two games by 31 and 45 points.

Georgia is simply too dominant of a force right now and it will be hard for Kentucky to rally itself to pull off the upset after its brutal Week 2 loss.

A 30-3, 33-7-type win seems to be in the cards for UGA given everything it has done to Kentucky in recent years.

Jaxson Dart built a strong foundation for a Heisman Trophy campaign in Weeks 1 and 2.

The Ole Miss quarterback produced 795 passing yards in the opening two wins of the season.

Only Texas State's Jordan McCloud, who played his third game on Thursday, has more passing yards in the FBS than Dart.

Dart's prowess in the pocket should show once again in Week 3 against a Wake Forest defense that allowed 31 points and 357 passing yards to the Virginia Cavaliers in Week 2.

Just like Kentucky's loss to South Carolina, Wake's Week 2 defeat to Virginia was stunning because the Cavaliers did not have huge expectations going into 2024.

Dart has four pass-catchers with more than 100 receiving yards already and two Ole Miss running backs are over the 100-yard mark on the ground.

If the offensive numbers were not convincing enough to pick Ole Miss, its defense has allowed three points in two games.

Ole Miss has not played great opposition, but it's still impressive to put up such a low number early in the season when focus can drift away against lesser opponents.

The Oklahoma Sooners reside in the biggest look-ahead spot in the Top 25 in Week 3.

Oklahoma is one week away from opening its SEC slate against the Tennessee Volunteers in Norman, a primetime game that will likely receive the College GameDay treatment.

The Sooners looked sluggish in their Week 2 win over the Houston Cougars and they could struggle to create separation against the Tulane Green Wave on Saturday.

Tulane just pushed the Kansas State Wildcats at home in Week 2.

The Green Wave lost after K-State's second-half comeback, but they put the Wildcats on upset alert for three quarters.

The Green Wave's quarterback-running back duo of Darian Mensah and Makhi Hughes thrived against K-State and it has potential to test Oklahoma.

Mensah threw for 342 yards and two scores in Week 2, while Hughes ran for 128 yards and a touchdown.

Oklahoma's offense was stuck in neutral against Houston one week after scoring 51 points on the Temple Owls.

The Sooners were outgained 318-249 by Houston and a similar stat line could come about on Saturday against a more talented Tulane team.

Oklahoma is more than capable of winning by more than two touchdowns, but last week's performance combined with the importance of Week 4's game could make it vulnerable to another close game.

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