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After three weeks of unpredictable results in the SEC, Week 4 brings a slate with four games between ranked opponents and several compelling narratives. The action kicks off with a top-15 showdown and concludes with a ranked battle under the lights.
No. 1 Texas at No. 14 Tennessee
Odds: Texas -4.5
Where to watch: Saturday, Sept. 26, at 11 a.m. CT on ABC
Prediction: Texas 28, Tennessee 20
ESPN's College GameDay will originate from Knoxville for this massive ranked showdown. The Volunteers' true freshman quarterback Faizon Brandon has impressed early, but he faces a star-studded Longhorns defense. Can the young gunslinger rise to the occasion?
South Alabama at Kentucky
Odds: Kentucky -20.5
Where to watch: Saturday, Sept. 26, at 11:45 a.m. CT on SEC Network
Prediction: South Alabama 13, Kentucky 45
Oklahoma at No. 2 Georgia
Odds: Georgia -13.5
Where to watch: Saturday, Sept. 26, at 2:30 p.m. CT on ESPN
Prediction: Oklahoma 10, Georgia 27
No. 4 Ole Miss at No. 21 Florida
Odds: Florida -3.5
Where to watch: Saturday, Sept. 26, at 2:30 p.m. CT on ABC
Prediction: Ole Miss 38, Florida 35
After securing a historic win over their former head coach, the No. 4 Rebels travel to The Swamp to face the No. 21 Gators. Florida head coach Jon Sumrall notched his first SEC win in Week 3, but a massive challenge awaits in Heisman frontrunner Trinidad Chambliss.
Vanderbilt at Auburn
Odds: Auburn -9.5
Where to watch: Saturday, Sept. 26, at 3:15 p.m. CT on SEC Network
Prediction: Vanderbilt 21, Auburn 27
South Carolina at No. 8 Alabama
Odds: Alabama -12.5
Where to watch: Saturday, Sept. 26, at 6 p.m. CT on ESPN
Prediction: South Carolina 21, Alabama 31
No. 23 Texas A&M at No. 10 LSU
Odds: LSU -9.5
Where to watch: Saturday, Sept. 26, at 6:30 p.m. CT on ABC
Prediction: Texas A&M 17, LSU 31
Can the Aggies get off the mat and take a swing at the Tigers? That is the question for Texas A&M, as they face their second consecutive night game in Death Valley. Head coach Mike Elko has a 2-0 record against LSU as Texas A&M's head coach, but he will be leading his squad against an LSU team also looking to bounce back from a loss to Ole Miss in Week 3.
No. 19 Missouri at No. 24 Mississippi State
Odds: Mississippi State -6.5
Where to watch: Saturday, Sept. 26, at 6:45 p.m. CT on SEC Network
Prediction: Missouri 31, Mississippi State 38
Cowbells, Kamario Taylor, and a night game in Starkvegas are on tap Saturday night, as the Bulldogs duel the No. 19 Tigers in the first ranked-versus-ranked matchup in Davis Wade Stadium since 2017.
Tulsa at Arkansas
Odds: Arkansas -7.5
Where to watch: Saturday, Sept. 26, at 7 p.m. CT on SEC Network+
Prediction: Tulsa 17, Arkansas 24
2026 record: 39-3
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Originally reported by aggieswire.