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Sean McVay disclosed on Monday that Davante Adams has a ruptured hamstring, an injury that necessitates surgery and will keep the star receiver out for 6 to 10 weeks. The setback occurred late in the Rams' 18-16 home defeat to the Arizona Cardinals in Week 6, with just over a minute remaining, when Adams pulled up with a non-contact injury to his left leg.
As he ran a route toward the end zone, Adams decelerated into a limping jog and glanced back as though he had been struck. Such reactions often indicate a severe tear or strain, and unfortunately, that proved to be the case.
Adams' extended absence is poised to trigger a fantasy domino effect for the 2-4 Rams. Here are the players to monitor closely.
WR Davante Adams, Los Angeles Rams
Adams paces Los Angeles in receiving yards (480), yards per reception (16.0), and receiving touchdowns (four). He also ranks fifth in the NFL in total fantasy points in half-PPR leagues (81.6). Losing him for a prolonged period is a bitter pill for fantasy managers, and the initial impact will likely be felt in Week 7 when the Rams face the Las Vegas Raiders—Adams' former team—a bottom-10 defense. Even without Adams, the team still boasts an elite pass-catching option.
WR Puka Nacua, Los Angeles Rams
Nacua has appeared in only four of a possible six contests in 2026 due to a pre-hernia injury that kept him out of Weeks 2 and 3, yet he still leads the Rams in receptions (37), targets (52), and yards after catch (206). He also leads the NFL in targets per game (13) and ranks second among receivers in fantasy points per game (20.8), trailing only Jaxon Smith-Njigba (24.2). Adams' absence may open even more targets for the 2025 Offensive Player of the Year, but it should also draw greater defensive attention and leave less room to operate. Given Nacua's upper-echelon talent as a pass-catcher and his steady, elite production, his fantasy floor remains high.
RB Kyren Williams, Los Angeles Rams
In the Rams' Week 6 loss to the Cardinals, Williams carried the ball only 10 times, a season low. When asked about the team's offensive struggles, he said: "I can't tell you, bro. Probably because I'm not out there." His frustration is evident, and losing three of four games likely doesn't help. That said, Williams is expected to be a significant fantasy producer once again in Week 7 as the Rams move forward without Adams. The Raiders surrender the seventh-most fantasy points on average to running backs, and prior to the Cardinals game, Williams was the RB5 in fantasy. What makes the 26-year-old especially dangerous, particularly in PPR formats, is his receiving production. He is currently tied for first in the NFL in receptions (27) among running backs alongside Jahmyr Gibbs.
TE Tyler Higbee, Los Angeles Rams
Higbee delivered his strongest fantasy performance of the 2026 season (16.2 points) when Nacua was out in Week 3. With Adams sidelined, his volume and production could see a similar uptick. Although Higbee didn't generate much in Week 6—four catches for 22 yards and a lost fumble—the Raiders allow the sixth-most fantasy points per game to tight ends (14.4). Coupled with the fact that he's the fourth-most targeted receiver on the team (now third), Higbee makes for a solid streaming option this Sunday.
WR Konata Mumpfield, Los Angeles Rams
Another player who benefited from Nacua's earlier absence was Konata Mumpfield. In Weeks 2 and 3, his snap rate was 71%, compared to 26.75% in the games Nacua played. Mumpfield can't replicate Adams' elite route-running and red-zone proficiency, but he can serve as a viable intermediate-to-downfield threat, as he's second on the team in yards per catch (15.9), slightly behind Adams (16.0). The second-year man out of Pittsburgh could certainly see a bump in volume.
QB Matt Stafford, Los Angeles Rams
As has been the case throughout his career, Matt Stafford is throwing the ball a lot in 2026. In fact, he leads the league in total attempts (1,794) and attempts per game (41.5). He's also seventh in touchdown passes at 11, connecting with eight different receivers. Clearly, he's comfortable spreading the ball to many targets, signifying that even without Adams, he's capable of finding the open man.