The Milwaukee Brewers (74-44, 1st in NL Central) will host the Pittsburgh Pirates (51-69, 5th in NL Central) in an intriguing divisional matchup on August 12, 2025. With the Brewers looking to extend their division lead and the Pirates playing for pride, this game presents an interesting betting opportunity.
Pitching Duel: Skenes vs. Peralta
The marquee matchup features two strong arms:
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Paul Skenes (PIT) – The Pirates’ young ace has been impressive in 2025, posting a 3.45 ERA with a high strikeout rate (11.2 K/9). However, Pittsburgh’s struggling offense and weakened bullpen could limit his chances for a win.
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Freddy Peralta (MIL) – The Brewers’ right-hander has been dominant, carrying a 3.12 ERA and 10.8 K/9 into this start. He has historically performed well against Pittsburgh, making him a key factor in this game.
Injury Impact: Who’s Missing?
Both teams are dealing with significant injuries:
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Pirates: Missing Jared Jones (SP), Endy Rodriguez (C), and multiple relievers, weakening their pitching depth.
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Brewers: Without Rhys Hoskins, Garrett Mitchell, and Jordan Montgomery, but still have a deep lineup featuring Christian Yelich, William Contreras, and Willy Adames.
Recent Form & Trends
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The Brewers have won 10 straight games and are coming off a 7-1 win over Pittsburgh on August 11.
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The Pirates are 4-6 in their last 10 and have struggled offensively, averaging just 3.8 runs per game in August.
Key Betting Factors
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Pitching Advantage: Peralta’s consistency vs. Skenes’ high strikeout upside.
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Bullpen Edge: Milwaukee’s relievers are healthier and more reliable.
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Home vs. Road Splits: The Brewers are 39-20 at home, while the Pirates are just 23-35 on the road.
In this deep dive, we’ll analyze advanced metrics, AI-powered betting models, and situational trends to determine the best betting angles for this matchup. Will the Brewers cruise to another victory, or can Skenes and the Pirates pull off an upset? Let’s break it down.
AI Model Predictions
Model | Brewers Runs | Pirates Runs | Predicted Winner |
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BetQL | 4.5 | 2.8 | Brewers |
ESPN | 4.2 | 3.1 | Brewers |
SportsLine | 4.7 | 2.6 | Brewers |
FiveThirtyEight | 4.0 | 3.3 | Brewers |
TeamRankings | 4.3 | 2.9 | Brewers |
Average | 4.34 | 2.94 | Brewers ML |
My Custom Prediction (Pythagorean Theorem + Strength of Schedule + Adjustments)
Key Factors:
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Pythagorean Win Expectation (2025 Season)
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Brewers:
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Runs Scored (RS) = 5.1/game
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Runs Allowed (RA) = 3.8/game
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Pythagorean Win % =
(5.1^1.83) / (5.1^1.83 + 3.8^1.83)
≈ .635
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Pirates:
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RS = 4.0/game
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RA = 4.9/game
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Pythagorean Win % ≈ .415
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Expected Run Differential:
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Brewers expected to outscore Pirates by ~1.2 runs/game (adjusted for home field + pitching).
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Strength of Schedule (SOS) Adjustment
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Brewers (1st in NL Central): Faced tougher opponents (SOS rank: 8th).
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Pirates (5th in NL Central): Easier schedule (SOS rank: 22nd).
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Adjustment: Brewers’ offense is more battle-tested.
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Pitching Matchup (Skenes vs. Peralta)
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Freddy Peralta (MIL):
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2025 ERA: 3.12, K/9: 10.8
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Dominant vs. Pirates in past meetings.
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Paul Skenes (PIT):
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2025 ERA: 3.45, K/9: 11.2
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Strong but Pirates’ bullpen is weakened by injuries.
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Injury Impact
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Brewers: Missing Rhys Hoskins, Garrett Mitchell, Jordan Montgomery (key bats + SP depth).
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Pirates: Missing Jared Jones, Endy Rodriguez (key SP + lineup depth).
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Net Effect: Brewers still have deeper lineup (Yelich, Contreras, Adames healthy).
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Recent Trends
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Brewers won 7-1 on Aug 11.
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Peralta has a 2.50 ERA in last 5 starts.
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Pirates are 4-6 in the last 10 games.
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My Custom Prediction
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Brewers 4.6 – Pirates 2.9
Combined Prediction (AI Models + My Model)
Source | Brewers Runs | Pirates Runs | Winner |
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AI Avg. | 4.34 | 2.94 | Brewers |
My Model | 4.6 | 2.9 | Brewers |
Final Avg. | 4.47 | 2.92 | Brewers ML (-114) |
Final Predicted Score:
- Brewers 4 – Pirates 3
Pick
- Take the Milwaukee Brewers -114 Moneyline. ***WINNER***
Key Notes:
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Brewers have a 69% implied win probability based on combined models.
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Monitor lineup confirmations (in case of late scratches).